BASIC CLINICAL RADIOBIOLOGY
Athens • Greece
23-27 September 2012
Early rate deadline: 22 June 2012
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Course Director
Albert van der Kogel, Radiation Biologist, Radboud University Nijmegen Medical Center (NL)
Teachers
Wolfgang Dörr, Radiation Biologist, UK Carl Gustav Carus, Dresden (DE)
Vincent Grégoire, Radiation Oncologist, UCL Cliniques Universitaires St Luc, Brussels (BE)
Michael Joiner, Radiation Biologist, Dept. of Radiation Oncology, Wayne State University, Detroit (USA)
Marianne Koritzinsky, Radiation Biologist, University Health Network, Toronto (CA)
Dorota Gabryś, Radiation Oncologist, Maria Skłodowska Curie Memorial Cancer Center and Institute of Oncology, Gliwice, (PL)
Local Organiser
Vassilios Kouloulias
Course aim
The aim is to provide an introduction to radiation biology as applied to radiotherapy. It will cover the basic mechanisms of cell death/survival and the radiation response of tumours and normal tissues. Formulas of tissue tolerance will be explained. The biological basis for current approaches to the improvement of radiotherapy will be described including novel fractionation schemes, retreatment, IMRT, modification of hypoxia, hadron therapy, combined radiotherapy/chemotherapy and biological modifiers of tumour and normal tissue effects.
Target Group
The course is aimed at trainees in radiotherapy, radiation oncologists who recognize a lack of basic radiobiological science or want to update their knowledge (i.e. for CME), medical physicists who wish to familiarize themselves with this field, physicians from other disciplines administering ionizing radiation, and RTTs.
Educational programme
A series of basic lectures introducing molecular and clinical radiobiology
- Radiobiology and (retreatment) tolerance of normal tissues
- Mechanisms and models or radiation cell killing
- The linear-quadratic approach to fractionation
- Molecular basis of radiation response
- Radiobiology and tolerance of normal tissues to (re)treatment
- Alternative fractionation schedules in radiotherapy
- Tumor hypoxia and the microenvironment
- Combined radiotherapy and chemotherapy
- The volume and dose-rate effect in radiotherapy
- Biological response modifiers and molecular approaches to therapy
- Protons and other particles in radiotherapy
- Radiation-induced malignancies